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| Caption | Ym1 crystal location in the Ncf1tm1Hbd/Ncf1tm1Hbd mouse. Dorsal view of lungs from 10 month old wild-type (A) and Ncf1tm1Hbd/Ncf1tm1Hbd (B) mice. The pale areas at the periphery of B are sites of consolidation with a chronic inflammatory cell infiltrate composed predominantly of macrophages surrounding crystals. C: Electron micrograph of the mutant mouse lung shows intracytoplasmic, needle-shaped crystals within alveolar macrophages (D). A 6-month old mutant mouse with chronic liver and skin abscesses had crystals within the bile ducts (E) and adjacent to bacteria in the skin (F). | ||||
| Copyright | This image is from Harbord M, J Biol Chem 2002 Feb 15;277(7):5468-75 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74593 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/05/2024 MGI 6.24 |
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