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Phenotype Image Detail
Image
Caption Histology of the retina. A: Retina from a wild-type female, with normal architecture, including inner nuclear layer (INL), outer nuclear layer (ONL), ganglion cell layer (GCL), and photoreceptors (PhR). B: Retina from a Clcn2tm1Mlv/Clcn2tm1Mlv female, with decreased outer nuclear layer, and a single row of photoreceptor nuclei remaining adjacent to the inner nuclear layer. C: Retina from a mutant male, which has lost all of the photoreceptor nuclei, leaving only the inner nuclear layer.
Copyright This image is from Nehrke K, J Biol Chem 2002 Jun 28;277(26):23604-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:77673
Associated
Alleles
Symbol Name
Clcn2tm1Mlv chloride channel, voltage-sensitive 2; targeted mutation 1, James E Melvin
Associated
Genotypes
Allelic Composition Genetic Background
Clcn2tm1Mlv/Clcn2tm1Mlv involves: C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory