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Phenotype Image Detail
Image
Caption A and B: Mouse embryos at 10.5 dpc. All Ncoa6tm1Jxu/Ncoa6tm1Jxu (-/-) embryos are smaller than wild-type (+/+) and Ncoa6tm1Jxu/Ncoa6+ embryos at this stage. Large blood pool in hearts (*) and pericardial effusion (arrow) were found in some mutant embryos (B). C and D: Cross-sections of hearts showing abnormal mutant heart morphologies, including the thin ventricular wall (arrows) and detachment of the endocardium (*).
Copyright This image is from Kuang SQ, J Biol Chem 2002 Nov 22;277(47):45356-60 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:80175
Associated
Alleles
Symbol Name
Ncoa6tm1Jxu nuclear receptor coactivator 6; targeted mutation 1, Jianming Xu
Associated
Genotypes
Allelic Composition Genetic Background
Ncoa6tm1Jxu/Ncoa6tm1Jxu involves: 129S6/SvEvTac * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory