Phenotype Image Detail

Image

Caption

Morphological analysis of colons from Slc26a3^tm1Sole/Slc26a3^tm1Sole mice. Fig. 3I: Colon dilatation shows the distended proximal (panels A and C) and distal (panel B) colons of Slc26a3^tm1Sole/Slc26a3^tm1Sole mice and the proximal colon in a wild-type mouse (panel D) immediately after death and dissection. Arrows point to the colon in each panel. Scale bar = 0.5 cm. Fig. 3II: Whole mount preparation of the colon mucosal surface. Panels A-C and panel D show the mucosal surface of mutant and wild-type mice, respectively, stained with methylene blue. Panels A and B are x40 magnification. Scale bar = 500 um. Panels C and D are shown at x100 magnification. Scale bars = 100 um. Panel E demonstrates serial sectioning (8 um) through conjoined crypts. Panel E is shown at x100 magnification. Scale bars = 100 um.

This image is from Schweinfest CW, J Biol Chem 2006 Dec 8;281(49):37962-71 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:117587

Associated
Alleles

Symbol	Name
Slc26a3^tm1Sole	solute carrier family 26, member 3; targeted mutation 1, Manoocher Soleimani

Associated
Genotypes

Allelic Composition	Genetic Background
Slc26a3^tm1Sole/Slc26a3^tm1Sole	involves: 129S6/SvEvTac * C57BL/6

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