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Phenotype Image Detail
Image
Caption Lung histology of E18.5 fetal wild-type, Abca3tm1Dgen/Abca3+, and Abca3tm1Dgen/Abca3tm1Dgen littermates. Paraffin sections of lungs from three E18.5 littermates of an Abca3tm1Dgen/Abca3+ cross were stained with hematoxylin and eosin. a, wild-type mouse had normal lung histology. b, Abca3tm1Dgen/Abca3+ mouse had thicker septa compared with wild-type mouse. c, Abca3tm1Dgen/Abca3tm1Dgen mouse lung was less well developed than either wild-type or heterozygous mice. Scale bar, 50 um.
Copyright This image is from Cheong N, J Biol Chem 2007 Aug 17;282(33):23811-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:124809
Associated
Alleles
Symbol Name
Abca3tm1Dgen ATP-binding cassette, sub-family A member 3; targeted mutation 1, Deltagen
Associated
Genotypes
Allelic Composition Genetic Background
Abca3tm1Dgen/Abca3tm1Dgen involves: 129P2/OlaHsd * C57BL/6J
Abca3tm1Dgen/Abca3+ involves: 129P2/OlaHsd * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory