| Image |
|
||||
| Caption | Loss of ABCA12 causes neonatal lethality and epidermal hyperkeratosis. A, Abca12tm1Lex/Abca12tm1Lex (Abca12 -/-) day 18.5 embryos (E18.5) when kept hydrated are similar in size and weight to wild-type (Abca +/+) littermates, but after exposure to air rapidly dry out and become encased in a collodion-like shell (B). The mutant epidermis displays a markedly thickened, hyperkeratotic epidermis as shown in hematoxylin and eosin stained skin sections; scale bar, 20 um (C) (sc, stratum corneum; sg, stratum granulosum; ss, stratum spinosum; sb, stratum basale). | ||||
| Copyright | This image is from Zuo Y, J Biol Chem 2008 Dec 26;283(52):36624-35 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:144062 | ||||
|
Associated Alleles |
|
||||
|
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
Analysis Tools