Phenotype Image Detail

Image

Caption

Testicular morphology of wild-type versus Hsf2^tm1Miv/Hsf2^tm1Miv and Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv mice. Testes recovered from adult (12-week old) wild-type (+/+), Hsf2^tm1Miv/Hsf2^tm1Miv (hsf2-/-), or Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv (hsf1-/-/hsf2-/-) mice were inspected macroscopically. Note the dramatic reduction in testicular size in the double homozygous mice compared to wild-type. x10.

This image is from Wang G, Genesis 2004 Feb;38(2):66-80, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:88035

Associated
Alleles

Symbol	Name
Hsf1^tm1Miv	heat shock factor 1; targeted mutation 1, Nahid F Mivechi
Hsf2^tm1Miv	heat shock factor 2; targeted mutation 1, Nahid F Mivechi

Associated
Genotypes

Allelic Composition	Genetic Background
Hsf2^tm1Miv/Hsf2^tm1Miv	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Hsf1^tm1Miv/Hsf1^tm1Miv Hsf2^tm1Miv/Hsf2^tm1Miv	involves: 129S2/SvPas * 129X1/SvJ * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24