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| Caption | Phenotype of Myh11tm2Peri/Myh11tm2Peri mice. (A) (Upper) Comparison of bladder (square 1), alimentary tract (square 2) including stomach (square 3), and the kidney (square 4) in wild-type (SM2+/+) and Myh11tm2Peri/Myh11tm2Peri (SM2-/-) mice (20 days). Note the retention of urine in the renal pelvis of the mutant kidney. (Lower) Development end-stage hydronephrosis with severe retention of urine in the renal pelvis in 25-day mutant mice and kidneys in age-matched wild-type mice. (B) (Upper) Comparison of neonatal and peri-mortal mutant with age-matched wild-type bladders. (Lower) Histology (40x) of peri-mortal mutant and age-matched wild-type bladders. | ||||
| Copyright | This image is from Chi M, Proc Natl Acad Sci U S A 2008 Nov 25;105(47):18614-8. Copyright 2008 National Academy of Sciences, U.S.A. J:142230 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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