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| Caption | (A-D) Scanning electron micrographs of stereocilia from 6 week old wild-type (Actg1+/+, A,B) and 6 week old Actg1tm1.1Erv/Actg1tm1.1Erv (Actg1-/-, C,D) mice. (E-H) Scanning electron microscopy images of OHC (outer hair cell) stereocilia from 16 week old wild-type (E,F) and mutant (G,H) mice. There is a loss of individual stereocilia from all three rows of OHC hair bundle form mutant mice. Images are from the middle turn of the cochlea. (I) Box and whisker plot (whiskers, maximum and minimum; box, 5th-95th percentile; line, mean) of the number of individual stereocilia in individual OHC bundles from wild-type or mutant mice at 6 and 16 weeks of age, *P<0.005. (J-K) Enlargements of image in (H) with arrows, indicating missing and shortened stereocilia. Scale bars A,C,E and G, 5um; B,D,F,H,J and K, 1um. | ||||
| Copyright | This image is from Belyantseva IA, Proc Natl Acad Sci U S A 2009 Jun 16;106(24):9703-8. Copyright 2009 National Academy of Sciences, U.S.A. J:150067 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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