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Image
Caption Gross and pathologic anatomy of disseminated S. xylosus infection in Ncf1tm1Shl/Ncf1tm1Shl mice. (A) An abscess of the left hindpaw (arrow) of a 15 week old Ncf1tm1Shl/Ncf1tm1Shl female mouse. This mouse also had cutaneous abscesses of the right periauricular soft tissue and the right forepaw. The lesions were fluctuant and grew S. xylosus in culture. (B) Necropsyy of the mouse shown in A. A 5-mm pyogranuloma of the right caudal lobe of the lung is indicated (arrow). (C) Multinucleated giant cells were found throughout the inflammatory lung tissue indicated in B. Characteristic granulomatous inflammation was found interspersed with acute inflammation (hematoxylin and eosin stain, x630).
Copyright This image is from Jackson SH, J Exp Med 1995 Sep 1;182(3):751-8, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:28267
Associated
Alleles
Symbol Name
Ncf1tm1Shl neutrophil cytosolic factor 1; targeted mutation 1, Steven M Holland
Associated
Genotypes
Allelic Composition Genetic Background
Ncf1tm1Shl/Ncf1tm1Shl involves: 129S2/SvPas * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory