Phenotype Image Detail

Image

Caption

Wild-type versus Sptbn1^tm1Mish/Spnb2⁺ BWS-like phenotype. A-D, gross comparison of wild-type (A, left) versus mutant Spnb2^tm1Mish/Spnb2⁺ (Beta2SP^+/-, A, right) mouse, wild-type (B, left) versus mutant (B, right) tongue, wild-type (C, left) versus mutant (C, right) kidney, wild-type (D, left) versus mutant (D, right) ear. E, wild-type (left) versus mutant (right) liver. F, wild-type (left) versus mutant (right) spleen. G, wild-type (left) versus mutant (right) stomach. H, wild-type (left) versus mutant (right) lung. I, wild-type (left) versus mutant (right) testis. J, wild-type (left) versus mutant (right) brain. K, wild-type (left) versus mutant (right) heart.

This image is from Yao ZX, J Biol Chem 2010 Nov 12;285(46):36112-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166879

Associated
Alleles

Symbol	Name
Sptbn1^tm1Mish	spectrin beta, non-erythrocytic 1; targeted mutation 1, Lopa Mishra

Associated
Genotypes

Allelic Composition	Genetic Background
Sptbn1^tm1Mish/Sptbn1⁺	involves: 129S6/SvEvTac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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