Phenotype Image Detail

Image

Caption

Wild-type versus Sptbn1^tm1Mish/Spnb2⁺ BWS-like phenotype. A-D, gross comparison of wild-type (A, left) versus mutant Spnb2^tm1Mish/Spnb2⁺ (Beta2SP^+/-, A, right) mouse, wild-type (B, left) versus mutant (B, right) tongue, wild-type (C, left) versus mutant (C, right) kidney, wild-type (D, left) versus mutant (D, right) ear. E, wild-type (left) versus mutant (right) liver. F, wild-type (left) versus mutant (right) spleen. G, wild-type (left) versus mutant (right) stomach. H, wild-type (left) versus mutant (right) lung. I, wild-type (left) versus mutant (right) testis. J, wild-type (left) versus mutant (right) brain. K, wild-type (left) versus mutant (right) heart.

This image is from Yao ZX, J Biol Chem 2010 Nov 12;285(46):36112-20 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166879

Associated
Alleles

Symbol	Name
Sptbn1^tm1Mish	spectrin beta, non-erythrocytic 1; targeted mutation 1, Lopa Mishra

Associated
Genotypes

Allelic Composition	Genetic Background
Sptbn1^tm1Mish/Sptbn1⁺	involves: 129S6/SvEvTac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24