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| Caption | (A) Representative figures of a terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Increase of TUNEL-positive apoptotic cells (red) in the Prkdctm1.1Bpcc/ Prkdctm1.1Bpcc (DNA-PKcs3A/3A) intestinal crypt (outlined with dashed lines). Nuclei were counterstained with DAPI (blue). Bar, 50 um. (B) Skin hyperpigmentation is clearly distinguishable in the mutant footpad and tail. (C) Hematoxylin and eosin staining of tail skin section. Massive melanin accumulated in the mutant epidermis and was abolished in a p53-null background. Bar, 20 um. | ||||
| Copyright | This image is from Zhang S, J Cell Biol 2011 Apr 18;193(2):295-305, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:171351 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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