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Phenotype Image Detail
Image
Caption Phenotypic appearance of a Ppcd1/0 mouse. Enucleated eyes were fixed in 10% formalin in phosphate-buffered saline and photographed. A. Appearance of Ppcd1/0 (PPCD1) mouse, showing the enlarged anterior chamber. B. Comparison of normal (left) and mutant (right) eyes. Corneal neovasculation can be observed on the surface of the mutant cornea. The arrow indicates an anterior synechia. Age, 3 months. C. Mutant eye, showing corneal haze and cell growth across the surface of the pupil (arrow). Age, 3 months. D. Mutant eye, showing lens subluxation, corneal haze, exudate in the anterior chamber, and anterior synechia. Age, 5 months.
Copyright This image is from Shen AL, PLoS One 2010;5(8):, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:164007
Associated
Alleles
Symbol Name
Ppcd1 posterior polymorphous corneal dystrophy 1
Associated
Genotypes
Allelic Composition Genetic Background
Ppcd1/+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Ppcd1/+ D2.129-Ppcd1

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory