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| Caption | (C) Morphology of reproductive organs from 8 week old wild-type (Ing2+/+) and Ing2tm1.1Ccha/Ing2tm1.1Ccha (Ing2-/-) male mice. The seminal vesicles (black arrowheads), bladder (white arrows), epididymis (white arrowheads), testes (black arrows) are demonstrated. Scale bar, 1 cm. (D) Testis weight during postnatal development of wild-type and mutant mice. Student's t test, n = 5 per group. Error bars are s.e.m. (E) Semen in wild-type and mutant mice. Scale bars, 100 um. (F) Numbers of normal spermatozoa in semen during postnatal development of wild-type and mutant mice. Data ae mean from n = 3 (8 weeks) or n = 2 (16 and 24 weeks). Error bars are s.e.m. (G) Normal and abnormal spermatozoa from wild-type and mutant mice, respectively. The leftmost panel (wild-type) shows mature normal spermatozoon with a characteristic, hook-shaped nucleus, straight mitochondrial sheath and straight tail. The right three panels (mutant) show morphologically abnormal, immature spermatozoa, including ones with a round head and a short tail (black arrow), a large head and multiple tails (white arrow), and a tail coiled (white arrowhead). Scale bars are 50 um in the left three panels and 25 um in the rightmost panel. | ||||
| Copyright | This image is from Saito M, PLoS One 2010;5(11):e15541, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:167311 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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