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Phenotype Image Detail
Image
Caption Neuron-derived Sema3e restricts vascular pathfinding in developing retinas. C) Whole-mount PECAM-1 IHC in P4 retinas. In the Sema3etm1Ddg/Sema3etm1Ddg (Sema3e-/-) retina, the vascular network is disorganized in the upper-right quadrant. Note the attachment of hyaloid vessels to the retinal surface (arrowhead). Scale bars: 100 um (C).
Copyright This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
Associated
Alleles
Symbol Name
Sema3etm1Ddg sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; targeted mutation 1, David D Ginty
Associated
Genotypes
Allelic Composition Genetic Background
Sema3etm1Ddg/Sema3etm1Ddg involves: 129P2/OlaHsd * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory