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| Caption | KDM4D promotes cardiac hypertrophy in response to transverse aortic constriction (TAC)-induced pressure overload. (B) H&E stains of paraffin section of wild-type (WT) and Tg(Myh6-KDM4A)BZpl/0 (Jmjd2a Tg) mouse hearts 3 weeks after sham and TAC operations. (C) Heart weight/body weight (HW/BW) ratio (n = 6-7 per group) and (D) relative areas of cardiomyocytes (n = 3-4 per group) in wild-type and mutant sham- and TAC-operated animals. The HW/BW ratio after TAC operation was increased 50% compared with sham operation in WT mice, whereas it was increased 100% in Tg mice. Values are mean +/- SEM. *P<0.05. | ||||
| Copyright | This image is from Zhang QJ, J Clin Invest 2011 Jun 1;121(6):2447-56 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173908 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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