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Phenotype Image Detail
Image
Caption (C) Whole-mount immunohistochemistry (IHC) for platelet/endothelial cell adhesion molecule (PECAM1) in Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem Tg(Tek-cre)#Rwng/0 (Tie2CreTg/WTRhojTg/Tg) embryos and control Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem (R26-RhojTg/Tg) embryos, at 10.5 dpc. Mutant embryos at 10.5 dpc demonstrate growth retardation with defective vascular development.
Copyright This image is from Fukushima Y, J Clin Invest 2011 May 2;121(5):1974-85 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:173943
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Akiyoshi Uemura
Tg(Tek-cre)#Rwng transgene insertion, Rong Wang
Associated
Genotypes
Allelic Composition Genetic Background
Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem
Tg(Tek-cre)#Rwng/0
involves: C57BL/6 * CBA

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory