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| Caption | Adult male Mirc5tm1Jae/Mirc5tm1Jae (mir-290-295-/-) testes show reduced germ cells compared with wild-type testes, whereas adult female mutant ovaries are atrophied. (A) Ovaries and reproductive tracts from 8-wk-old wild-type (WT) and Mirc5tm1Jae/Mirc5tm1Jae females. (Scale bar, 1 mm.) (B-E) Hematoxylin and eosin-stained ovary sections from adult WT (B and D) and mutant (C and E) animals. (Scale bars, 100 uM.) (F) Testes from 8-wk-old WT and mutant males. Note that the smaller testes size of the knockout male is at least partially due to the smaller body weight of the knockout animal. (Scale bar, 1 mm.) (G-J) Periodic acid-Schiff (PAS)-stained testes sections from adult WT (G and I) and mutant (H and J) males. Black rectangle in H highlights area with empty seminiferous tubules. (Scale bars, 100 uM.) | ||||
| Copyright | This image is from Medeiros LA, Proc Natl Acad Sci U S A 2011 Aug 23;108(34):14163-8. Copyright 2011 National Academy of Sciences, U.S.A. J:175228 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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