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| Caption | (A) Representative fluorescein angiography (FA), indocyanine green angiogram (ICGA), and fundus images of Tg(BEST1-HTRA1)#Ybf/0 and wild-type (WT) littermates. The mutant mice exhibited hyperfluorescent lesions on ICGA (red arrowheads) and orange-yellow lesions on the fundus photograph (red circles). (B) Higher magnification shows polypoidal, grape-cluster structure (Upper) or loop structure (lower, red arrowhead) of ICGA lesions in mutant mice. (C) FA of an 11-mo-old mutant mouse showed speckled hyperfluorescence at the same site of an ICGA lesion (red circles), resembling occult choroidal neovascularization (CNV). (D) Composite ICGA image shows the distribution of lesions in mutant mice. | ||||
| Copyright | This image is from Jones A, Proc Natl Acad Sci U S A 2011 Aug 30;108(35):14578-83. Copyright 2011 National Academy of Sciences, U.S.A. J:175227 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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