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Phenotype Image Detail
Image
Caption (C) Histological analysis showing that Mapk14tm3.1(Mapk11)Nbr/Mapk14tm2Nbr Edil3Tg(Sox2-cre)1Amc/0 Mapk11tm1Jsca/Mapk11tm1Jsca (p38alphaKI/delta p38betaKO) embryos have similar cardiac defects as the Mapk14tm2Nbr/Mapk14tm2Nbr Edil3Tg(Sox2-cre)1Amc/0 Mapk11tm1Jsca/Mapk11tm1Jsca double knock-out embryos.
Copyright This image is from del Barco Barrantes I, Proc Natl Acad Sci U S A 2011 Aug 2;108(31):12764-9. Copyright 2011 National Academy of Sciences, U.S.A. J:176023
Associated
Alleles
Symbol Name
Edil3Tg(Sox2-cre)1Amc EGF-like repeats and discoidin I-like domains 3; transgene insertion 1, Andrew P McMahon
Mapk11tm1Jsca mitogen-activated protein kinase 11; targeted mutation 1, J Simon C Arthur
Mapk14tm2Nbr mitogen-activated protein kinase 14; targeted mutation 14, Angel R Nebreda
Mapk14tm3.1(Mapk11)Nbr mitogen-activated protein kinase 14; targeted mutation 3.1, Angel R Nebreda
Associated
Genotypes
Allelic Composition Genetic Background
Mapk11tm1Jsca/Mapk11tm1Jsca
Mapk14tm2Nbr/Mapk14tm3.1(Mapk11)Nbr
Edil3Tg(Sox2-cre)1Amc/Edil3+ 		involves: 129P2/OlaHsd * C57BL/6 * CBA
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory