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Phenotype Image Detail
Image
Caption At 8 weeks of age wild-type (WT) mice exhibit clear lenses (A) in contrast to total cataracts observed in Srebf2lop13/Srebf2lop13 eyes (B). Histological analysis of lens sections from WT lenses (C) revealed highly organized fiber cells while swollen fiber cells (arrow) and bladder cells (arrowhead) were identified in mutant lenses (D). At the posterior of the mutant lenses (F) morgagnian globules and liquefied lens material (asterisk) were noted. Clear and organized lens structures were observed in WT lenses (E).
Copyright This image is from Merath KM, Mamm Genome 2011 Aug 21;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:176249
Associated
Alleles
Symbol Name
Srebf2lop13 sterol regulatory element binding factor 2; lens opacity 13
Associated
Genotypes
Allelic Composition Genetic Background
Srebf2lop13/Srebf2lop13 STOCK Srebf2lop13/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory