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| Caption | Paint-filled inner ears of wild-type (Zeb1+/+), Zeb1tm2Yhi/Zeb1+ (Zeb1deltaEx1/+), Zeb1tm2Yhi/Zeb1tm2Yhi (Zeb1deltaEx1/deltaEx1) and Zeb1tm2Yhi/Zeb1Tw (Zeb1deltaEx1/Tw) mice at E14.5 are shown from lateral (A-D), medial (E-H), ventral (I-L) and dorsal (M-P) views. Inner ears from wild-type and Zeb1tm2Yhi/Zeb1+ mice appeared similar and normal. Zeb1tm2Yhi/Zeb1tm2Yhi lateral semicircular canals had a subtle constriction (indicated by *) of the midportion of the canal that differed from those observed in Zeb1Tw/Zeb1+ mice. The lateral semicircular canals of Zeb1tm2Yhi/Zeb1Tw mice did not contain this abnormality and resemble those of Zeb1Tw/Zeb1+ mice. Zeb1tm2Yhi/Zeb1+ mice have normal ABR thresholds (Q). a, anterior semicircular canal; c, cochlear duct; es, endolymphatic sac; l, lateral semicircular canal; p, posterior semicircular canal; s, saccule; u, utricle. | ||||||
| Copyright | This image is from Kurima K, PLoS Genet 2011 Sep;7(9):e1002307, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:177274 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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