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Phenotype Image Detail
Image
Caption (F) Transmission electron microscopy of ultrathin sections from distal sciatic nerve stumps 14 days after nerve crush injury in Col1a1tm1(CAG-Sirt2)Jmi/Col1a1tm1(CAG-Sirt2)Jmi Tg(Mpz-cre)26Mes/0 (Sirt2-SCTG) and Col1a1tm1(CAG-Sirt2)Jmi control mouse. Arrows point to regenerated fibers. Note thinner compact myelin sheaths around axons from the Sirt2-SCTG preparation. (Scale bar: 2 um.)
Copyright This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468
Associated
Alleles
Symbol Name
Col1a1tm1(CAG-Sirt2)Jmi collagen, type I, alpha 1; targeted mutation 1, Jeffrey Milbrandt
Tg(Mpz-cre)26Mes transgene insertion 26, Albee Messing
Associated
Genotypes
Allelic Composition Genetic Background
Col1a1tm1(CAG-Sirt2)Jmi/Col1a1+
Tg(Mpz-cre)26Mes/0 		involves: 129S4/SvJae * C57BL/6 * FVB/N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory