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| Caption | Histological analysis of wild-type and Tfap2dtm1Mos/Tfap2dtm1Mos mesencephalon. (a, b) Hematoxylin-eosin staining on midbrain paraffin sections of 1.5 month old mice. The arrows mark the colliculus inferior, which is absent in Tfap2dtm1Mos/Tfap2dtm1Mos mice. (c-f) Immunohistological analysis with Tfap2d (Ap-2delta; c, d) and Tfap2a (Ap-2alpha; e, f) -specific antibodies on sagittal sections from 3 week old mice midbrains. Tfap2d expression is restricted to the colliculus inferior and, to a lesser extent, to the colliculus superior and the dorsal thalamus. Tfap2a is expressed in the colliculus superior and the cerebellum of wild-type animals. In Tfap2dtm1Mos/Tfap2dtm1Mos mice, the expression of Tfap2a extends throughout the entire mesencephalon. | ||||
| Copyright | This image is from Hesse K, PLoS One 2011;6(8):e23483, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:177585 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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