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| Caption | B, H&E (HE) staining (panels a-h) and naphthol and ASD chloroacetate esterase (NACE) staining of granulopoietic cells (panels i-l). The spleen from a 445-day-old Inca1tm1Cmt/Inca1tm1Cmt (Inca1-/-) mouse showed a disorganized structure of the white pulp ("w" in panels b and f), an increased number of megakaryocytes (arrowheads in panels f and j), and prominent extramedullary hematopoiesis (arrows in panel j hint at red-stained granulocytes). Other spleens also tested in the kinase assays depicted in Fig. 5C were represented by the spleens of the 420-day-old pair of mice, which did not differ significantly concerning their while pulp structure (w in panels c and d, g and h) and the occurrence of megakaryocytes (arrowheads in panels k and l) or extramedullary hematopoiesis, respectively. Marked areas in panels a-d are shown with higher magnifications in panels e-h. | ||||
| Copyright | This image is from Baumer N, J Biol Chem 2011 Aug 12;286(32):28210-22 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:175667 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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