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Phenotype Image Detail
Image
Caption (C) Siaetm1.2Avrk/Siaetm1.2Avrk (Siaedelta2/delta2) mice show histological features of glomerulonephritis. Paraffin embedded sections of kidney from mutant and wild-type (C57BL/6) mice were stained with hematoxylin and eosin (top) and with periodic acid Schiff (PAS) reagent (bottom). The glomeruli of the mutant mice (top right) show mesangial hypercellularity and expansion caused by periodic acid Schiff-positive deposits (bottom). The magnification is marked on each image. Bars, 100 um.
Copyright This image is from Cariappa A, J Exp Med 2009 Jan 16;206(1):125-38, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:144035
Associated
Alleles
Symbol Name
Siaetm1.2Avrk sialic acid acetylesterase; targeted mutation 1.2, Ajit Varki
Associated
Genotypes
Allelic Composition Genetic Background
Dock2m1Hsd/Dock2m1Hsd
Siaetm1.2Avrk/Siaetm1.2Avrk
B6NHsd.Cg-Siaetm1.2Avrk Dock2m1Hsd

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory