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Phenotype Image Detail
Image
Caption (A) Conditional knock-out of Ndfip1 in Ndfip1tm1Sest/Ndfip1tm1Sest Tg(Nes-cre)1Kln/0 (Nestin-Cre+(KO)) mice increases total infarct size 24h after hypoxia-ischemia. 2,3,5-triphenyltetrazolium choloride (TTC)-stained brain slices show a larger infarct area (unstained white tissue) in mutant (Nestin-Cre+(KO)) versus control (Nestin-Cre-(WT)) littermates for all ischemic regions examined (cortex, striatum, hippocampus, and thalamus). Bar, 2 mm.
Copyright This image is from Howitt J, J Cell Biol 2012 Jan 9;196(1):29-36, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:180657
Associated
Alleles
Symbol Name
Ndfip1tm1Sest Nedd4 family interacting protein 1; targeted mutation 1, Seong-Seng Tan
Tg(Nes-cre)1Kln transgene insertion 1, Rudiger Klein
Associated
Genotypes
Allelic Composition Genetic Background
Ndfip1tm1Sest/Ndfip1tm1Sest
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory