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Phenotype Image Detail
Image
Caption c, d: Wild-type testis sections. e: Wild-type epididymis with sperm. f, g: Testis sections from confirmed Prdm9M1045Lja/Prdm9+ mice exhibit complete spermatogenic block, with an absence of elongated spermatids. h: Epididymis from confirmed heterozygous mutant contains a small number of round germ cells and no sperm. i, j: Testis section from a confirmed Prdm9M1045Lja/Prdm9M1045Lja mutant exhibits severe germ cell loss. k: Epididymis from a homozygous mutant is devoid of germ cells.
Copyright This image is from Weiss J, Mamm Genome 2012 Jan 19;(): and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:179895
Associated
Alleles
Symbol Name
Prdm9M1045Lja PR domain containing 9; mutation 1045, J Larry Jameson
Associated
Genotypes
Allelic Composition Genetic Background
Prdm9M1045Lja/Prdm9M1045Lja involves: C57BL/6J * DBA
Prdm9M1045Lja/Prdm9+ involves: C57BL/6J * DBA

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory