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Phenotype Image Detail
Image
Caption (A) Crossing the Gt(ROSA)26Sortm3(CAG-Il17a)Awai allele to the delete-cre strain yields Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor+ (Del-IL17ind/+) mice. Skin inflammation, stunted growth, and failure to thrive is a consistent phenotype in all Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor+ mice observed when compared with delete-cre littermate controls (Del).
Copyright This image is from Haak S, J Clin Invest 2009 Jan;119(1):61-9 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144710
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai gene trap ROSA 26, Philippe Soriano; targeted mutation 3.1, Ari Waisman
Associated
Genotypes
Allelic Composition Genetic Background
Gt(ROSA)26Sortm3.1(CAG-Il17a)Awai/Gt(ROSA)26Sor+ involves: BALB/c * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory