Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Lack of Pold1 3'-5' exonuclease activity causes tumors. (A) Swollen thymus in 4-month old Pold1^tm1Uchi/Pold1^tm1.1Uchi mice. Th: thymus, H: heart (B) Tail with nodule in 14-month old Pold1^tm1Uchi/Pold1^tm1.1Uchi mice.

This image is from Uchimura A, PLoS ONE 2009;4(1):e4184, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:144992

Associated
Alleles

Symbol	Name
Pold1^tm1.1Uchi	polymerase (DNA directed), delta 1, catalytic subunit; targeted mutation 1.1, Arikuni Uchimura
Pold1^tm1Uchi	polymerase (DNA directed), delta 1, catalytic subunit; targeted mutation 1, Arikuni Uchimura

Associated
Genotypes

Allelic Composition	Genetic Background
Pold1^tm1Uchi/Pold1^tm1.1Uchi	C57BL/6-Pold1^tm1Uchi/Pold1^tm1.1Uchi

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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