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Phenotype Image Detail
Image
Caption Cd68tm1Xfen/Cd68tm1Xfen (-/-) mice have increased trabecular bone and decreased trabecular tissue mineral density. (A) Representative trabecular micro-computed tomography (uCT) images from 6-month-old female mice of each genotype (5 mice per group). (B) uCT analysis of distal femoral trabecular bone revealed that Cd68tm1Xfen/Cd68tm1Xfen mice have increased bone volume (BV/TV), increased trabecular number (TB. N), decreased trabecular spacing (Tb. Sp.) and decreased trabecular tissue mineral density (Trabecular TMD). There was no significant difference in trabecular thickness (Tb. Th.). (C) Representative cortical uCT images from each genotype. (D) Quantification of measured parameters. There was no significant difference between genotypes in either cortical thickness (Ct. Th.) or cortical tissue mineral density (Cortical TMD). *, p<.05; **, p<.01. Data presented are means + standard deviation.
Copyright This image is from Ashley JW, PLoS One 2011;6(10):e25838, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:178120
Associated
Alleles
Symbol Name
Cd68tm1Xfen CD68 antigen; targeted mutation 1, Xu Feng
Associated
Genotypes
Allelic Composition Genetic Background
Cd68tm1Xfen/Cd68tm1Xfen C57BL/6J-Cd68tm1Xfen

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory