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| Caption | Enhanced destabilization of the medial meniscus (DMM)-induced osteoarthritis cartilage destruction in Cytl1tm1Chun/Cytl1tm1Chun mice. A, Wild-type (WT) and Cytl1tm1Chun/Cytl1tm1Chun (KO) mice were subjected to a sham operation (control) or destabilization of the medial meniscus (DMM) surgery to induce osteoarthritis (OA) cartilage destruction. Articular cartilage was stained with Safranin-O. The images at right are enlarged versions of the marked region in the left images. Scale bar: 400um. B, Mankin score in WT and KO mice after sham operations and DMM surgery. Values represent means +/-S.E. (n = 16). C, immunohistochemical staining of Col2a1 and Prg4 in joint articular cartilage of WT and KO mice after sham operation and DMM surgery. Scale bar: 400um. D, Safranin-O staining (left) and Makin score (right) of 10-month-old WT and KO mice joint articular cartilage. Scale bar: 400um. Values represent means +/- S.E. (n = 6). *, p<0.05. | ||||
| Copyright | This image is from Jeon J, J Biol Chem 2011 Aug 5;286(31):27206-13 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:175377 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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