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| Caption | Sections through the cornea of Slc4a11tm1Boet/Slc4a11tm1Boet (Slc4a11-KO) (D) and wild-type (WT) mice (E) clearly reveal a significant thickening of the corneal stroma with disturbance of the stratification of the epithelium. Electron microscopy sections reveal a thickened Descement membrane and enlarged endothelial cells in Slc4a11tm1Boet/Slc4a11tm1Boet mice (F) compared with WT mice (G). Note intracellular vacuolation (arrows in F) in the endothelial cells of KO animals. d, Descement's membrane; e, epithelium; en, endothelium; st, stroma. Scale bars used are as follows: D and E, 50 um; F and G, 2 um. | ||||
| Copyright | This image is from Groger N, J Biol Chem 2010 May 7;285(19):14467-74 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:162968 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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