Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

Cochlear dysgenesis caused by loss of Fgf20 in the developing cochlear sensory epithelium. (B) Histology of the inner ear showing normal organ of Corti structure in wild-type and Fgf20^tm1.1Dor/Fgf20⁺ cochlea in which there are three outer hair cells (OHC), one inner hair cell (IHC), three Deiters' cells (DC), two pillar cells (PC), and several inner phalangeal cells (IPhC). Fgf20^tm1.1Dor/Fgf20^tm1.1Dor cochlea showed disorganization and loss of sensory cells in the organ of Corti. Scale bar: 100 um.

This image is from Huh SH, PLoS Biol 2012 Jan;10(1):e1001231, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:184501

Associated
Alleles

Symbol	Name
Fgf20^tm1.1Dor	fibroblast growth factor 20; targeted mutation 1.1, David M Ornitz

Associated
Genotypes

Allelic Composition	Genetic Background
Fgf20^tm1.1Dor/Fgf20^tm1.1Dor	involves: 129X1/SvJ * C57BL/6J

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