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| Caption | Arpc3Gt(XG476)Byg/Arpc3Gt(XG476)Byg (ARPC3-/-) fibroblast cells are deficient in lamellipodia formation. (A and B) Representative phase-contrast images showing the morphology of wild-type (ARPC3+/+, A) and homozygous mutant (B) fibroblast cells after 7 days of differentiation. Arrows indicate lamellipodia (wild-type) and filopodia-like protrusions (FLPs) (mutant). Bar, 50 um. (C and D) Time-lapse montage showing spreading morphology of wild-type (C) and mutant cells (D) on 5 mg/ml fibronectin-coated glass surface. Frame interval is 15 min. Bars, 15 um. | ||||
| Copyright | This image is from Suraneni P, J Cell Biol 2012 Apr 16;197(2):239-51, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:185040 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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