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| Caption | Gene trap disruption of Tnrc6a (GW182) leads to embryonic lethality and defects in the yolk sac. A, comparison of control (gt/+) embryos and Tnrc6aGt(XE786)Byg/Tnrc6aGt(XE786)Byg (gt/gt) embryos at E9.5 and E10.5. B, H&E staining and Ki67 immunolabeling of the yolk sac identified impaired hematopoiesis, abnormal endoderm, and reduced cell proliferation in mutant (GW182 gt/gt) embryos at E9.5. | ||||
| Copyright | This image is from Jiang Z, J Biol Chem 2012 Feb 17;287(8):5979-87 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:182447 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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