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| Caption | Loss of pancreatic beta-cells in aged Huwe1tm1Wgu/Y Tg(Ins2-cre)23Herr/0 mice. B, immunostaining of pancreases from the control (i-vi) and from the Huwe1tm1Wgu/Y Tg(Ins2-cre)23Herr/0 (arf-bp1FL/Y/RIP-cre) mice (vii-xii). i, iv, vii, and x, 1 month old mice; ii, v, viii, and xi, 6 month old mice; and iii, vi, ix, and xii, 9 month old mice. Antibodies against insulin (i-iii and vii-ix) and glucagon (iv-vi and x-xii) were used. Dotted circles in ix outline the islets. | ||||||
| Copyright | This image is from Kon N, J Biol Chem 2012 Feb 10;287(7):5102-11 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:182446 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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