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Phenotype Image Detail
Image
Caption Il33tm1Aki/Il33tm1Aki mice show reduced accumulation of eosinophils in the lungs after S. venezuelensis infection. (A) Histological analysis of lungs of wild-type (Il33+/+) and Il33tm1Aki/Il33tm1Aki (Il33-/-) mice was performed before (cont) and after S. venezuelensis infection (Sv). PAS, periodic acid-Schiff stain. (Scale bars, 100 um). After infection, wild-type mice develop eosinophilic inflammation and goblet-cell hyperplasia in the lungs at day 7, but mutant mice only modestly developed these changes.
Copyright This image is from Yasuda K, Proc Natl Acad Sci U S A 2012 Feb 28;109(9):3451-6. Copyright 2012 National Academy of Sciences, U.S.A. J:182160
Associated
Alleles
Symbol Name
Il33tm1Aki interleukin 33; targeted mutation 1, Shizuo Akira
Associated
Genotypes
Allelic Composition Genetic Background
Il33tm1Aki/Il33tm1Aki involves: 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory