About   Help   FAQ
Phenotype Image Detail
Image
Caption Role of Fcgr4 in rheumatoid arthritis. (A) The development of clinical signs of arthritis in wild-type and Fcgr4tm1.1Rav/Fcgr4tm1.1Rav (FcgammaRIV-/-) mice upon injection of KBxN serum. (B) Measurement of the area of immigrated innate immune effector cells into the joints of wild-type and mutant animals (n=4). An asterisk in A and B indicates a significant difference with a p-value less than 0.05. (C) Histological analysis of inflamed joints of wild-type and mutant animals.
Copyright This image is from Nimmerjahn F, Proc Natl Acad Sci U S A 2010 Nov 9;107(45):19396-401. Copyright 2010 National Academy of Sciences, U.S.A. J:167375
Associated
Alleles
Symbol Name
Fcgr4tm1.1Rav Fc receptor, IgG, low affinity IV; targeted mutation 1.1, Jeffrey V Ravetch
Associated
Genotypes
Allelic Composition Genetic Background
Fcgr4tm1.1Rav/Fcgr4tm1.1Rav involves: C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory