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Phenotype Image Detail
Image
Caption A, confocal microscopy images showing the presence of misshapen nuclei in Lmnatm7Lgf/Lmnatm7Lgf (LmnaLAO/LAO) cells (stained with a lamin A antibody). Typical nuclei from wild-type (Lmna+/+) and Lmnatm6Lgf/Lmnatm6Lgf (LmnaPLAO/PLAO) fibroblasts are shown for comparison.
Copyright This image is from Coffinier C, J Biol Chem 2010 Jul 2;285(27):20818-26 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165928
Associated
Alleles
Symbol Name
Lmnatm7Lgf lamin A; targeted mutation 7, Loren G Fong
Associated
Genotypes
Allelic Composition Genetic Background
Lmnatm7Lgf/Lmnatm7Lgf involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory