Phenotype Image Detail

Image

Caption

Lafora bodies in tissues of Nhlrc1^{tm1(KOMP)Vlcg}/Nhlrc1^{tm1(KOMP)Vlcg} (Epm2b-/-) mice. Sections of brain, heart, and skeletal muscle were stained with periodic acid-Schiff/diastase to visualize alpha-amylase resistant polysaccharide, indicated by arrows. A, cerebellum, mutant; B, cerebellum, wild-type; C, hippocampus, mutant; D, hippocampus, wild-type; E, heart, mutant; F, heart, wild-type; G, soleus muscle, mutant; H, soleus muscle, wild-type.

This image is from DePaoli-Roach AA, J Biol Chem 2010 Aug 13;285(33):25372-81 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165994

Associated
Alleles

Symbol	Name
Nhlrc1^{tm1(KOMP)Vlcg}	NHL repeat containing 1; targeted mutation 1, Velocigene
Nhlrc1^{tm1(KOMP)Vlcg}	NHL repeat containing 1; targeted mutation 1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Nhlrc1^{tm1(KOMP)Vlcg}/Nhlrc1^{tm1(KOMP)Vlcg}	involves: C57BL/6J * C57BL/6NTac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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