Phenotype Image Detail

Image

Caption

Lafora bodies in tissues of Nhlrc1^{tm1(KOMP)Vlcg}/Nhlrc1^{tm1(KOMP)Vlcg} (Epm2b-/-) mice. Sections of brain, heart, and skeletal muscle were stained with periodic acid-Schiff/diastase to visualize alpha-amylase resistant polysaccharide, indicated by arrows. A, cerebellum, mutant; B, cerebellum, wild-type; C, hippocampus, mutant; D, hippocampus, wild-type; E, heart, mutant; F, heart, wild-type; G, soleus muscle, mutant; H, soleus muscle, wild-type.

This image is from DePaoli-Roach AA, J Biol Chem 2010 Aug 13;285(33):25372-81 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:165994

Associated
Alleles

Symbol	Name
Nhlrc1^{tm1(KOMP)Vlcg}	NHL repeat containing 1; targeted mutation 1, Velocigene
Nhlrc1^{tm1(KOMP)Vlcg}	NHL repeat containing 1; targeted mutation 1, Velocigene

Associated
Genotypes

Allelic Composition	Genetic Background
Nhlrc1^{tm1(KOMP)Vlcg}/Nhlrc1^{tm1(KOMP)Vlcg}	involves: C57BL/6J * C57BL/6NTac

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24