Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

D, quantification of plaque load in the cortex and hippocampus of App^tm3.1Zhe/App^tm3.1Zhe Psen1^tm1Mpm/Psen1^tm1Mpm (APP/hAbeta/mutC PS1 M146V/M146V), App^tm3.1Zhe/App^tm3.1Zhe Psen1^tm1Mpm/App⁺ (APP/hAbeta/mutC PS1 M146V/+), and App^tm1Ck/App^tm1Ck Psen1^tm1Mpm/Psen1^tm1Mpm (APP/hAbeta PS1 M146V/M146V) mice. ***, p < 0.001; N.S., non-significant (analysis of variance).

This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379

Associated
Alleles

Symbol	Name
App^tm3.1Zhe	amyloid beta precursor protein; targeted mutation 3.1, Hui Zheng
Psen1^tm1Mpm	presenilin 1; targeted mutation 1, Mark P Mattson

Associated
Genotypes

Allelic Composition	Genetic Background
App^tm3.1Zhe/App^tm3.1Zhe Psen1^tm1Mpm/Psen1^tm1Mpm	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24