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Phenotype Image Detail
Image
Caption D shows islet immunohistochemistry, and islets from wild-type (hadh+/+; a and b) and Hadhtm1Csta/Hadhtm1Csta (hadh-/-; c and d) are shown. Insulin is stained green, glucagon is red, and nuclear is blue. Glucagon-staining alpha-cells are distributed throughout the islet in mutants, rather than being restricted to the outer margin as in wild-type mice.
Copyright This image is from Li C, J Biol Chem 2010 Oct 8;285(41):31806-18 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166803
Associated
Alleles
Symbol Name
Hadhtm1Csta hydroxyacyl-Coenzyme A dehydrogenase; targeted mutation 1, Charles A Stanley
Associated
Genotypes
Allelic Composition Genetic Background
Hadhtm1Csta/Hadhtm1Csta involves: 129S1/Sv * 129X1/SvJ * NIH Black Swiss

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory