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Phenotype Image Detail
Image
Caption Rassf5tm1Sblee/Rassf5tm1Sblee (Rassf5-/-) mice are resistant to TNF-alpha-induced apoptosis. B, Rassf5 wild-type (Rassf5+/+) and mutant mice were injected with TNF-alpha as in A, and all of the animals were sacrificed at 6 hours before death (n = 3 for each genotype). Paraffin-embedded sections of liver were analyzed by H&E and TUNEL staining. Control liver (Rassf5+/Rassf5tm1Sblee; Rassf5+/-) from an uninjected animal is shown.
Copyright This image is from Park J, J Biol Chem 2010 Nov 5;285(45):35029-38 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166871
Associated
Alleles
Symbol Name
Rassf5tm1Sblee Ras association (RalGDS/AF-6) domain family member 5; targeted mutation 1, Sean Lee
Associated
Genotypes
Allelic Composition Genetic Background
Rassf5tm1Sblee/Rassf5tm1Sblee involves: 129S6/SvEvTac * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory