Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

Both the Vps18^tm1.1Wtao/Vps18⁺ Tg(Nes-cre)1Kln/0 (Vps18^F/+; Nestin-Cre) and Vps18^tm1.1Wtao/Vps18^tm1.1Wtao (Vps18^F/F) control mice grow normally. Vps18^tm1.1Wtao/Vps18^tm1.1Wtao Tg(Nes-cre)1Kln/0 (CKO) mice display severe postnatal growth retardation and are smaller at P10.

This image is from Peng C, J Biol Chem 2012 Aug 1;(): and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:186307

Associated
Alleles

Symbol	Name
Tg(Nes-cre)1Kln	transgene insertion 1, Rudiger Klein
Vps18^tm1.1Wtao	VPS18 CORVET/HOPS core subunit; targeted mutation 1.1, Wufan Tao

Associated
Genotypes

Allelic Composition	Genetic Background
Vps18^tm1.1Wtao/Vps18^tm1.1Wtao Tg(Nes-cre)1Kln/0	involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6 * SJL

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24