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| Caption | Expanded spongiotrophoblast layer in heterozygous Plac1tm1(KOMP)Vlcg/Plac1+ females that inherit the mutant allele from the mother (Xm-X) and in homozygous Plac1tm1(KOMP)Vlcg/Plac1tm1(KOMP)Vlcg females that inherit one mutant allele from the mother and the other mutant allele from the father (Xm-Xp-). Spongiotrophoblasts in wild-type (WT fem) and Plac1 mutant placentae. In situ hybridization of Prl8a8 expression using a digoxygenin detection system. Non-specific signal was determined by hybridization with the "sense" riboprobe construct (magnification = 1.5x). Prl8a8 staining confirms the expansion of the spongiotrophoblasts in females that inherit the mutant allele from the mother. | ||||||
| Copyright | This image is from Jackman SM, Mol Reprod Dev 2012 Aug;79(8):564-72, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:186550 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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