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| Caption | External phenotype and skeletal and somite defects in Pofut1cax/Pofut1cax mice. (A-C) Examples of homozygous mutants demonstrating the variable phenotype in the backcross progeny. (D-G) Skeletal preparations of E15.5 embryos showing that even externally apparently normal mice have skeletal defects (D), and demonstrating various defects such as split vertebrae (asterisks in D, F, G), rib fusions and bifurcations (arrowheads in F), reduced or missing pedicles (arrows in G), and axial truncations (E). White and black boxes in (E) indicate the regions shown enlarged in (F) and (G), respectively. (H, I) Sections of E9.5 mutant embryos showing distinct somite borders (indicated by arrowheads) and somites of variable size. | ||||||
| Copyright | This image is from Schuster-Gossler K, BMC Dev Biol 2009;9():6, an open-access article, licensee BioMed Central Ltd. J:145608 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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