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Phenotype Image Detail
Image
Caption (a) Hematoxylin and eosin analysis of heterozygous Bmpertm1Cpat/Bmper+ (HT) lungs demonstrated delayed branching morphogenesis and inadequate expanded alveoli, which were separated by expansive interstitial mesenchyme. (b) Staining for the type II epithelial cell marker prosurfactant C (arrows). Bars, 100 uM. Positive staining is brown and counterstaining is blue. Graphical representation of the percentage of prosurfactant C-positive cells in wild-type versus heterozygous mutant lungs.
Copyright This image is from Kelley R, J Cell Biol 2009 Feb 23;184(4):597-609, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:146800
Associated
Alleles
Symbol Name
Bmpertm1Cpat BMP-binding endothelial regulator; targeted mutation 1, Cam Patterson
Associated
Genotypes
Allelic Composition Genetic Background
Bmpertm1Cpat/Bmper+ involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory