Phenotype Image Detail

Image

Caption

B, Morphological features of tumors derived from 14-week old female Tg(MMTV-PyVT)634Mul/0 [PyVT(+/-)/ADN(+/+)] and Tg(MMTV-PyVT)634Mul/0 Adipoq^tm1Chan/Adipoq⁺ [PyVT(+/-)/ADN(+/-)] mice of the FVB/N background. Distinct morphologies were observed between tumors collected from mice with normal and reduced adiponectin levels. Note that central necrosis and geographic tumor necrosis, as well as stromal lymphocytic responses represented the typical basal-like subtype of breast tumors in PyVT(+/-)/ADN(+/-) mice.

This image is from Lam JB, PLoS ONE 2009;4(3):e4968, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:147458

Associated
Alleles

Symbol	Name
Adipoq^tm1Chan	adiponectin, C1Q and collagen domain containing; targeted mutation 1, Lawrence Chan
Tg(MMTV-PyVT)634Mul	transgene insertion 634, William Muller

Associated
Genotypes

Allelic Composition	Genetic Background
Adipoq^tm1Chan/Adipoq⁺ Tg(MMTV-PyVT)634Mul/0	FVB.Cg-Adipoq^tm1Chan Tg(MMTV-PyVT)634Mul

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24