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| Caption | Gross phenotype of Tgm3tm1Sjo/Tgm3tm1Sjo (-/-) mice. Southern blot analysis of tail biopsies from mice born of heterozygous interbreeding showed that homozygous mutants were born at the expected Mendelian ratios (A). The pelage hair of homozygous animals at 4 weeks of age showed a distinctive wavy pattern (B and C). This became less obvious as the mice matured (D). While gross hair abnormalities disappear with time, irregularities in the vibrissae, which are evident perinatally (E, mutant; F, control at P5) persist throughout life. Expression of Tgm3 is observed in pelage hair in the medulla and in the inner root sheath (G). | ||||
| Copyright | This image is from John S, PLoS One 2012;7(4):e34252, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:187109 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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